ERBB4 anticorps (C-Term)

N° du produit ABIN213439

Cet anticorps Lapin Polyclonal détecte spécifiquement ERBB4 dans IHC et IHC (p). Il présente une réactivité avec des échantillons de Humain et Singe.

Aperçu rapide pour ERBB4 anticorps (C-Term) (ABIN213439)

Antigène: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERBB4 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ERBB4 anticorps

Épitope: C-Term

Specificité: Human ERBB4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ERBB3 (60 % ).

Homologie: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Pig, Platypus (93%) Bat, Opossum (87%) Turkey, Chicken (80%).

Purification: Immunoaffinity purified

Immunogène: Synthetic 15 amino acid peptide from C-terminus of human ERBB4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Pig, Platypus (93%), Bat, Opossum (87%), Turkey, Chicken (80%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (30 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 30-60 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ERBB4

Antigène: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Autre désignation: ERBB4 / HER4

Sujet: Name/Gene ID: ERBB4
Subfamily: EGF Receptor
Family: Protein Kinase

Synonyms: ERBB4, ERBB 4, HER4, p180 erb4, p180erbB4

ID gène: 2066

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway