HHV DNA Polymerase Catalytic Subunit (AA 1131-1235) anticorps (Alexa Fluor 350)

N° du produit ABIN2175765

Détail du produit

Antigène: HHV DNA Polymerase Catalytic Subunit

Épitope: AA 1131-1235

Reactivité: Human Herpesvirus 1 (HHV-1), Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Specificité: This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit

Réactivité croisée: Virus

Réactivité croisée (Details): HHV1

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: HHV DNA Polymerase Catalytic Subunit

Classe de substances: Viral Protein

Sujet:

Synonyms: DPOL_HHV11, DNA polymerase catalytic subunit, UL30, HHV1gp046.

Background: Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.