IL-1 beta anticorps

N° du produit ABIN217587

Cet anticorps anti-IL-1 beta Polyclonal Lapin (ABIN217587) détecte spécifiquement IL-1 beta dans WB, ELISA et Func. L’anticorps est réactif avec des échantillons de Poulet.

Aperçu rapide pour IL-1 beta anticorps (ABIN217587)

Antigène: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivité: Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-1 beta est non-conjugé

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Détail du produit anti-IL-1 beta anticorps

Specificité: Recognizes chicken Interleukin 1 beta (chIL-1beta), which shares homology with mammalian IL-1beta. IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression. Chicken models indicate physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica. Neutralizes chicken IL-1 beta.

Purification: Affinity purified

Immunogène: Recombinant chicken IL-1.

Type of Immunogen: Recombinant protein

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA, Func, WB

Usage: Western Blot: LS-C43116 detects a band of approximately 29kD in HD-11 cell lysates transfected with chIL-1. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Chicken

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS.

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur IL-1 beta

Antigène: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Autre désignation: IL1B

Sujet: Name/Gene ID: IL1B
Family: IL-1

Synonyms: IL1B, IL-1B, IL-1 beta, IL1-BETA, Preinterleukin 1 beta, Pro-interleukin-1-beta, Catabolin, IL-1, IL1F2, Interleukin 1, beta, Interleukin-1 beta

ID gène: 3553

Pathways: Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome