TJP1 anticorps

N° du produit ABIN2192206

Détail du produit anti-TJP1 anticorps

Antigène: TJP1 (Tight Junction Protein 1 (TJP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TJP1 est non-conjugé

Application: Immunofluorescence (IF)

Stérilité: 0.2 μm filtered

Information d'application

Indications d'application: For immunfluorescence and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50..

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Références pour anticorps anti-TJP1 (ABIN2192206)

Balda, Anderson: "Two classes of tight junctions are revealed by ZO-1 isoforms." dans: The American journal of physiology, Vol. 264, Issue 4 Pt 1, pp. C918-24, (1993) (PubMed).

Détails sur TJP1

Antigène: TJP1 (Tight Junction Protein 1 (TJP1))

Autre désignation: Zona Occludens 1 (TJP1 Produits)

Synonymes: anticorps ZO-1, anticorps ZO1, anticorps zo1, anticorps tight junction protein 1, anticorps tight junction protein ZO-1, anticorps TJP1, anticorps Tjp1, anticorps LOC396567

Sujet: The polyclonal antibody recognizes human zona occludens 1 (ZO-1), an ~220 kDa tight junction protein belonging to the membrane-associated guanlyate kinase (MAGUK) family. Members of this family are involved in epithelial and endothelial intercellular junctions. They each contain at least one PSD95/Dlg/ZO-1 (PDZ) domain, a Src homology 3 (SH3) domain, and an enzymatically inactive guanylate kinase domain. PDZ domains are 90-amino acid protein-protein binding domains that recognize at least a 3-residue peptide motif in the COOH termini of their binding partners. PDZ domain- containing proteins, like ZO-1, typically act as scaffolding proteins that organize membrane receptors and cytosolic proteins into multimeric signaling complexes often at the sites of cell-cell contact. The effectiveness and

Pathways: Carbohydrate Homeostasis, Cell-Cell Junction Organization