RAD9A anticorps (AA 1125-1139)

N° du produit ABIN225443

L’anticorps Lapin Polyclonal anti-RAD9A a été validé pour WB et ELISA. Il convient pour détecter RAD9A dans des échantillons de Saccharomyces cerevisiae.

Aperçu rapide pour RAD9A anticorps (AA 1125-1139) (ABIN225443)

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD9A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RAD9A anticorps

Épitope: AA 1125-1139

Specificité: Detects Saccharomyces cerevisiae Rad9, a protein involved in the DNA damage checkpoint. In S. cerevisiae this checkpoint is mainly controlled by the PI(3) kinase-like kinase (PIKK) Mec1, which is activated in response to DNA damage. Activated Mec1 hyperphosphorylates Rad9, which in turn triggers the binding of Rad53, the ortholog of mammalian Chk2. Activated Rad53 specifically targets substrates required for cell cycle arrest, gene expression and efficient DNA repair. Mutations affecting Rad9 impair checkpoint induced cell-cycle arrest and increase genomic instability. Is pan reactive with both the phosphorylated and non-phosphorylated forms of this protein.

Purification: Purified

Immunogène: Synthetic peptide corresponding to aa 1125-1139 of yeast Rad9 protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA (1:2000 - 1:4000), WB (1:50 - 1:250)

Usage: Western Blot: LS-C42615 detects a band of approximately 60kD.

Commentaires:

Target Species of Antibody: Yeast

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.01 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur RAD9A

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Autre désignation: RAD9A / RAD9

Sujet: Name/Gene ID: RAD9A

Synonyms: RAD9A, HRAD9, RAD9, RAD9 homolog, RAD9 (S. pombe) homolog, RAD9 homolog A (S. pombe)

ID gène: 5883

UniProt: Q99638

Pathways: Positive Regulation of Response to DNA Damage Stimulus