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MEK1 anticorps (pSer218)

L’anticorps Lapin Polyclonal anti-MEK1 a été validé pour WB. Il convient pour détecter MEK1 dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN228872

Aperçu rapide pour MEK1 anticorps (pSer218) (ABIN228872)

Antigène

Voir toutes MEK1 (MAP2K1) Anticorps
MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivité

  • 337
  • 186
  • 179
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Humain, Souris, Rat

Hôte

  • 304
  • 31
  • 3
  • 2
  • 2
Lapin

Clonalité

  • 269
  • 73
Polyclonal

Conjugué

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Cet anticorp MEK1 est non-conjugé

Application

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Western Blotting (WB)
  • Épitope

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    pSer218

    Specificité

    Recognizes human MEK 1 and MEK 2, when phosphorylated at serine 218 and 222. MEK 1 and MEK 2 are also known as MAP2K1 and MAP2K2, respectively. Species cross-reactivity: mouse. Species sequence homology: rat, bovine, canine, chicken, xenopus, zebrafish, monkey.

    Purification

    Affinity purified

    Immunogène

    Synthetic phosphopeptide corresponding to an amino acid sequence which includes phosphorylated serine 218 and 222 within MEK1 and 2.

    Type of Immunogen: Synthetic phospho-peptide

    Isotype

    IgG
  • Indications d'application

    Approved: WB (1:1000)

    Usage: Suitable for use in Western Blot. Western Blot: 1:1000. Recognizes a band of ~45kD in Western Blots of serum stimulated NIH3T3 cell lysates. Positive control: NIH 3T3 cell lysate.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    10 mM HEPES,  pH 7.5, 0.01 % BSA, 0.1 % sodium azide, 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeat freeze-thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

    Autre désignation

    MAP2K1 / MEK1

    Sujet

    Name/Gene ID: MAP2K1
    Subfamily: MAP2K
    Family: Protein Kinase

    Synonyms: MAP2K1, ERK activator kinase 1, MAPK/ERK kinase 1, MAPKK 1, MKK1, PRKMK1, MEK 1, MAP kinase kinase 1, MAPKK1, MEK1

    ID gène

    5604

    UniProt

    Q02750

    Pathways

    Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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