EGFR anticorps (pTyr1068)

N° du produit ABIN232925

L’anticorps anti-EGFR Polyclonal Lapin est utilisé pour la détection de EGFR dans des échantillons de Humain et Rat. Il a été validé pour WB, IHC, ELISA et IHC (p).

Aperçu rapide pour EGFR anticorps (pTyr1068) (ABIN232925)

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGFR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-EGFR anticorps

Épitope: pTyr1068

Specificité: Recognizes endogenous levels of human EGF receptor at ~175kD only when phosphorylated at Tyr1068 at 175kD. The antibody may cross-react with other activated EGF receptor family members (e. g., ErbB2), and cross-reacts slightly with activated PDGF receptor.

Purification: Immunoaffinity purified

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding Tyr1068 of human EGF receptor (KLH).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA, IHC, IHC-P, WB (1:1000)

Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Western Blot: 1:1000. Immunohistochemistry (Paraffin): 1:50-350.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur EGFR

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Autre désignation: EGFR

Sujet: Name/Gene ID: EGFR
Subfamily: EGF Receptor
Family: Protein Kinase

Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1

ID gène: 1956

UniProt: P00533

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins