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WNT1 anticorps (Internal Region)

WNT1 Reactivité: Humain ELISA, WB Hôte: Lapin Polyclonal unconjugated
Pubmed (1 reference)
N° du produit ABIN233837
$658.50
Plus frais de port $45.00 et $20.00 pour carboglace
100 μg
Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables
  • Antigène Voir toutes WNT1 Anticorps
    WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
    Épitope
    • 15
    • 11
    • 11
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 74
    • 43
    • 12
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    Humain
    Hôte
    • 68
    • 6
    Lapin
    Clonalité
    • 68
    • 6
    Polyclonal
    Conjugué
    • 43
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WNT1 est non-conjugé
    Application
    • 45
    • 32
    • 18
    • 16
    • 14
    • 14
    • 12
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB)
     Réactivité croisée
    Humain, Rat (Rattus), Mouton, Chien, Macaque, Opossum (Didelphimorphia)
    Attributs du produit
    Concentration Definition: by UV absorbance at 280 nm
    Immunogène
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of human Wnt1 protein.
    Isotype
    IgG
  • Indications d'application
    This affinity purified antibody has been tested for use in ELISA and western blotting.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.38 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Banon-Maneus, Rovira, Ramirez-Bajo, Moya-Rull, Hierro-Garcia, Takenaka, Diekmann, Eickelberg, Königshoff, Campistol: "Wnt pathway activation in long term remnant rat model." dans: BioMed research international, Vol. 2014, pp. 324713, (2015) (PubMed).

  • Antigène
    WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
    Autre désignation
    Wnt1 (WNT1 Produits)
    Synonymes
    Xint-1, Xwnt1, int-1, int1, wnt-1, wnt1-a, Int-1, Wnt-1, sw, swaying, BMND16, INT1, OI15, Int1, WNT-1, sb:eu647, zgc:194464, zgc:194478, WNT1, Wnt family member 1, Wnt family member 1 L homeolog, wingless-type MMTV integration site family, member 1, WNT1, wnt1.L, Wnt1, wnt1
    Sujet
    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 (Wingless-type MMTV integration site family member 1) is a member of the WNT gene family. It is highly conserved in evolution and the protein encoded by this gene is known to be 98% identical to mouse Wnt1 protein at the amino acid level. Studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. Wnt1 is secreted as an extracellular matrix protein.
    Synonyms: INT1 antibody, Murine mammary tumor virus integration site 1 antibody, Oncogene INT1 antibody, Proto oncogene protein Wnt 1 antibody, Wingless type MMTV integration site family member 1 antibody
    ID gène
    7471, 4885655
    UniProt
    P04628
    Pathways
    Signalisation WNT, Dopaminergic Neurogenesis
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