NCOA3 anticorps

N° du produit ABIN964885

Détail du produit anti-NCOA3 anticorps

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA3 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with several isoforms of human NCOA3 protein (a, b, d, e and f).  A BLAST analysis was used to suggest cross-reactivity with NCOA3 from human and macaque sources based on a 100% homology with the immunizing sequence.  Expect partial reactivity with NCOA3 from dog, bovine, mouse and rat sources based on partial sequence homology.  Cross-reactivity with NCOA3 from other sources has not been determined.

Attributs du produit: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs),

Purification: affinity purified

Stérilité: Sterile filtered

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human NCOA3 isoform a protein.
Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and western blotting.

Commentaires:

Gene Name: NCOA3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.82 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.

Date de péremption: 3 months

Détails sur NCOA3

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Autre désignation: NCOA3 (NCOA3 Produits)

Synonymes: anticorps NCOA3, anticorps ACTR, anticorps AIB-1, anticorps AIB1, anticorps CAGH16, anticorps CTG26, anticorps KAT13B, anticorps RAC3, anticorps SRC-3, anticorps SRC3, anticorps TNRC14, anticorps TNRC16, anticorps TRAM-1, anticorps bHLHe42, anticorps pCIP, anticorps 2010305B15Rik, anticorps AW321064, anticorps Actr, anticorps Aib1, anticorps Rac3, anticorps Src3, anticorps Tram-1, anticorps Tram1, anticorps p/Cip, anticorps pCip, anticorps actr, anticorps aib-1, anticorps aib1, anticorps cagh16, anticorps ctg26, anticorps kat13b, anticorps pcip, anticorps rac3, anticorps src-3, anticorps src3, anticorps tnrc14, anticorps tnrc16, anticorps tram-1, anticorps xSRC-3, anticorps nuclear receptor coactivator 3, anticorps nuclear receptor coactivator 3 S homeolog, anticorps NCOA3, anticorps Ncoa3, anticorps ncoa3.S

Sujet: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs),
Synonyms: Nuclear receptor coactivator 3 NCoA-3 Thyroid hormone receptor activator molecule 1 TRAM-1, pCIP, bHLHe42 Receptor-associated coactivator 3, RAC-3 Amplified in breast cancer 1 protein, AIB-1 Steroid receptor coactivator protein 3, SRC-3

ID gène: 8202, 32307126

UniProt: Q9Y6Q9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha