ARL6IP1 anticorps

N° du produit ABIN2422671

Détail du produit anti-ARL6IP1 anticorps

Antigène: ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL6IP1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant protein of human ARL6IP1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ARL6IP1

Antigène: ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))

Autre désignation: ARL6IP1 (ARL6IP1 Produits)

Synonymes: anticorps arl6ip, anticorps MGC56593, anticorps zgc:56593, anticorps zgc:77873, anticorps ARL6IP, anticorps aip1, anticorps armer, anticorps ARL6IP1, anticorps MGC85055, anticorps MGC139614, anticorps DKFZp459O112, anticorps AIP1, anticorps ARMER, anticorps AIP-6, anticorps AL022945, anticorps AU042858, anticorps Aip-1, anticorps Arl6ip, anticorps C85138, anticorps mKIAA0069, anticorps ADP-ribosylation factor-like 6 interacting protein 1, anticorps ADP ribosylation factor like GTPase 6 interacting protein 1, anticorps ADP ribosylation factor like GTPase 6 interacting protein 1 L homeolog, anticorps ADP-ribosylation factor like GTPase 6 interacting protein 1, anticorps arl6ip1, anticorps ARL6IP1, anticorps arl6ip1.L, anticorps Arl6ip1

Sujet: ARMER (apoptotic regulator in the membrane of the endoplasmic reticulum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a multi-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regulated during myeloid differentiation. ARMER may play a role in membrane trafficking, protein transport or cell signaling during hematopoietic maturation.