PAX5 anticorps

N° du produit ABIN2426335

Détail du produit anti-PAX5 anticorps

Antigène: PAX5 (Paired Box 5 (PAX5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX5 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogène: Synthetic peptide of human PAX5

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PAX5

Antigène: PAX5 (Paired Box 5 (PAX5))

Autre désignation: PAX5 (PAX5 Produits)

Synonymes: anticorps PAX5, anticorps BSAP, anticorps Pax-5, anticorps pax5-a, anticorps RGD1565236, anticorps EBB-1, anticorps KLP, anticorps Pax[Zf-b], anticorps noi, anticorps pax2.1, anticorps pax2a, anticorps paxzf-b, anticorps paired box 5, anticorps paired box 5 L homeolog, anticorps PAX5, anticorps pax5.L, anticorps Pax5, anticorps pax5

Sujet: B cell lineage specific activator,B cell lineage specific activator protein,B cell specific activator protein,B cell specific transcription factor,B-cell-specific transcription factor,BSAP,EBB-1,KLP,Paired box 5,Paired box gene 5 (B cell lineage specific activator protein),Paired box gene 5 (B cell lineage specific activator),Paired box gene 5,Paired box homeotic gene 5,Paired box protein Pax 5,Paired box protein Pax-5,Paired domain gene 5,PAX 5,PAX5,PAX5,Transcription factor PAX 5,This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.

Poids moléculaire: Calculated MW: 42 kDa

NCBI Accession: NP_057953