ANKMY2 anticorps

N° du produit ABIN2429175

Détail du produit anti-ANKMY2 anticorps

Antigène: ANKMY2 (Ankyrin Repeat and MYND Domain Containing 2 (ANKMY2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKMY2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant protein of human ANKMY2

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ANKMY2

Antigène: ANKMY2 (Ankyrin Repeat and MYND Domain Containing 2 (ANKMY2))

Autre désignation: ANKMY2 (ANKMY2 Produits)

Synonymes: anticorps ZMYND20, anticorps AI035571, anticorps Gna14, anticorps ankmy2, anticorps si:dkeyp-25a3.5, anticorps fi46e08, anticorps wu:fi46e08, anticorps zgc:55491, anticorps ankyrin repeat and MYND domain containing 2, anticorps ankyrin repeat and MYND domain containing 2b, anticorps ankyrin repeat and MYND domain containing 2a, anticorps ANKMY2, anticorps Ankmy2, anticorps ankmy2b, anticorps ankmy2a

Sujet: ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.