Necdin-Like 2 anticorps

N° du produit ABIN2432595

Détail du produit anti-Necdin-Like 2 anticorps

Antigène: Necdin-Like 2 (NDNL2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Necdin-Like 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Synthetic peptide of human NDNL2

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:5000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Necdin-Like 2

Antigène: Necdin-Like 2 (NDNL2)

Autre désignation: NSMCE3 (NDNL2 Produits)

Synonymes: anticorps mage, anticorps zgc:101850, anticorps NDNL2, anticorps HCA4, anticorps MAGEG1, anticorps MAGEL3, anticorps NSE3, anticorps NSMCE3, anticorps 5730494G16Rik, anticorps AI642138, anticorps BB044375, anticorps Mageg1, anticorps mage-g1, anticorps NSE3 homolog, SMC5-SMC6 complex component, anticorps necdin-like 2, anticorps Nsmce3, anticorps ndnl2, anticorps NDNL2, anticorps NSMCE3

Sujet: The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).

Poids moléculaire: Calculated MW: 34 kDa

NCBI Accession: NP_619649