OMG anticorps

N° du produit ABIN2433503

Détail du produit anti-OMG anticorps

Antigène: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OMG est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Synthetic peptide of human OMG

Isotype: IgG

Information d'application

Indications d'application: IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur OMG

Antigène: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Autre désignation: OMG (OMG Produits)

Synonymes: anticorps OMGP, anticorps omgp, anticorps MGC107958, anticorps OMG, anticorps DKFZp459F1351, anticorps oligodendrocyte myelin glycoprotein, anticorps myelin oligodendrocyte glycoprotein, anticorps oligodendrocyte-myelin glycoprotein, anticorps OMG, anticorps MOG, anticorps Omg, anticorps omg

Sujet: Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells, from dorsal root ganglion explants in which growth cone collapse was observed, from rat retinal ganglion neurons, and from NG108 and PC-12 cells.

NCBI Accession: NP_002535

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size