PHLDA3 anticorps (N-Term)

N° du produit ABIN2452076

Détail du produit anti-PHLDA3 anticorps

Antigène: PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))

Épitope: AA 1-31, N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PHLDA3 est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific to human PHLDA3.

Réactivité croisée (Details): Not tested in other species.

Attributs du produit: The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.

Purification: Purified

Stérilité: Sterile filtered

Immunogène: Synthetic peptide corresponding to N terminal aa 1-31 of human PHLDA3

Clone: 4B6

Isotype: IgG2b kappa

Information d'application

Indications d'application: Other applications were not tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Agent conservateur: Azide free

Stock: -20 °C/-80 °C

Stockage commentaire: -20 C (For long term storage: -70 C)

Références pour anticorps anti-PHLDA3 (ABIN2452076)

Kawase, Ohki, Shibata, Tsutsumi, Kamimura, Inazawa, Ohta, Ichikawa, Aburatani, Tashiro, Taya: "PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt." dans: Cell, Vol. 136, Issue 3, pp. 535-50, (2009) (PubMed).

Détails sur PHLDA3

Antigène: PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))

Autre désignation: PHLDA3 (PHLDA3 Produits)

Synonymes: anticorps TIH1, anticorps Tih1, anticorps si:dz182n13.5, anticorps zgc:92333, anticorps pleckstrin homology like domain family A member 3, anticorps pleckstrin homology like domain, family A, member 3, anticorps pleckstrin homology-like domain, family A, member 3, anticorps PHLDA3, anticorps Phlda3, anticorps phlda3

Sujet: PHLDA3 (Pleckstrin homology-like domain family A member 3) is a small PH (Pleckstrin homology) domain-only protein (127 a.a. in human) that is highly conserved in vertebrates. Recently PHLDA3 was found to be a p53-regulated repressor of Akt hence it is speculated as a tumor suppressor. PHLDA3 also inhibits anchorage-independent cell growth. PHLDA3 gene is frequently lost in human lung endocrine tumors.

UniProt: Q9Y5J5