KIF2A anticorps

N° du produit ABIN2458064

Détail du produit anti-KIF2A anticorps

Antigène: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF2A est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KIF2A.

Information d'application

Indications d'application: KIF2A antibody can be used for detection of KIF2A by ELISA at 1:62500. KIF2A antibody can be used for detection of KIF2A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KIF2A antibody at -20 °C.

Détails sur KIF2A

Antigène: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Autre désignation: KIF2A (KIF2A Produits)

Synonymes: anticorps HK2, anticorps KIF2, anticorps C530030B14Rik, anticorps Kif2, anticorps Kns2, anticorps M-kinesin, anticorps kif2-a, anticorps fj55b02, anticorps wu:fj55b02, anticorps kinesin family member 2A, anticorps kinesin heavy chain member 2A L homeolog, anticorps kinesin heavy chain member 2A, anticorps zgc:103670, anticorps Kinesin-2, anticorps KIF2A, anticorps Kif2a, anticorps kif2a.L, anticorps zgc:103670, anticorps GL50803_17333, anticorps GL50803_16456

Sujet: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.

Poids moléculaire: 80 kDa

ID gène: 3796

NCBI Accession: NP_004511

UniProt: O00139

Pathways: Dynamique des Microtubules, Ribonucleoprotein Complex Subunit Organization