Angiomotin anticorps

N° du produit ABIN2458106

Détail du produit anti-Angiomotin anticorps

Antigène: Angiomotin (AMOT)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiomotin est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AMOT.

Information d'application

Indications d'application: AMOT antibody can be used for detection of AMOT by ELISA at 1:1562500. AMOT antibody can be used for detection of AMOT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AMOT antibody at -20 °C.

Détails sur Angiomotin

Antigène: Angiomotin (AMOT)

Autre désignation: AMOT (AMOT Produits)

Synonymes: anticorps C81439, anticorps CAG-2, anticorps D0Kist1, anticorps E230009N18Rik, anticorps Sii6, anticorps mKIAA1071, anticorps RGD1564027, anticorps si:dkey-13f9.6, anticorps wu:fj21a07, anticorps angiomotin, anticorps microRNA 4329, anticorps AMOT, anticorps Amot, anticorps MIR4329, anticorps amot

Sujet: AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 72 kDa

ID gène: 154796

NCBI Accession: NP_573572

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size