CHRNA4 anticorps

N° du produit ABIN2458123

Détail du produit anti-CHRNA4 anticorps

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA4 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNA4.

Information d'application

Indications d'application: CHRNA4 antibody can be used for detection of CHRNA4 by ELISA at 1:62500. CHRNA4 antibody can be used for detection of CHRNA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CHRNA4 antibody at -20 °C.

Détails sur CHRNA4

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Autre désignation: CHRNA4 (CHRNA4 Produits)

Synonymes: anticorps NACHRA4, anticorps BFNC, anticorps EBN, anticorps EBN1, anticorps NACHR, anticorps NACRA4, anticorps NARAC, anticorps Acra-4, anticorps Acra4, anticorps ENFL1, anticorps neuronal acetylcholine receptor subunit alpha-4, anticorps neuronal acetylcholine receptor subunit alpha-4-like, anticorps cholinergic receptor nicotinic alpha 4 subunit, anticorps cholinergic receptor, nicotinic, alpha 4b, anticorps cholinergic receptor, nicotinic, alpha polypeptide 4, anticorps CpipJ_CPIJ002434, anticorps LOC100368057, anticorps CHRNA4, anticorps chrna4b, anticorps Chrna4

Sujet: CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 67 kDa

ID gène: 1137

NCBI Accession: NP_000735

UniProt: P43681

Pathways: Synaptic Membrane