L3MBTL1 anticorps

N° du produit ABIN2458274

Détail du produit anti-L3MBTL1 anticorps

Antigène: L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L3MBTL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human L3MBTL.

Information d'application

Indications d'application: L3MBTL antibody can be used for detection of L3MBTL by ELISA at 1:1562500. L3MBTL antibody can be used for detection of L3MBTL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store L3MBTL antibody at -20 °C.

Détails sur L3MBTL1

Antigène: L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

Autre désignation: L3MBTL (L3MBTL1 Produits)

Synonymes: anticorps C630004G01, anticorps L3mbtl, anticorps mKIAA0681, anticorps H-L(3)MBT, anticorps L3MBTL, anticorps ZC2HC3, anticorps dJ138B7.3, anticorps RGD1307316, anticorps l(3)mbt-like (Drosophila), anticorps L3MBTL1, histone methyl-lysine binding protein, anticorps l(3)mbt-like 1 (Drosophila), anticorps L3mbtl1, anticorps L3MBTL1

Sujet: L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 86 kDa

ID gène: 26013

NCBI Accession: NP_056293

UniProt: Q9Y468

Pathways: Chromatin Binding