RBM5 anticorps

N° du produit ABIN2458330

Détail du produit anti-RBM5 anticorps

Antigène: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM5 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBM5.

Information d'application

Indications d'application: RBM5 antibody can be used for detection of RBM5 by ELISA at 1:312500. RBM5 antibody can be used for detection of RBM5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RBM5 antibody at -20 °C.

Détails sur RBM5

Antigène: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Autre désignation: RBM5 (RBM5 Produits)

Synonymes: anticorps wu:fc25a08, anticorps wu:fe06f12, anticorps g15, anticorps h37, anticorps luca15, anticorps rbm5, anticorps rmb5, anticorps RBM5, anticorps G15, anticorps LUCA15, anticorps RMB5, anticorps D030069N10Rik, anticorps RNA binding motif protein 5, anticorps RNA binding motif protein 5 S homeolog, anticorps RNA binding motif protein 5 L homeolog, anticorps rbm5, anticorps rbm5.S, anticorps RBM5, anticorps rbm5.L, anticorps Rbm5

Sujet: RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

Poids moléculaire: 92 kDa

ID gène: 10181

NCBI Accession: NP_005769

UniProt: P52756

Pathways: Ribonucleoprotein Complex Subunit Organization