Snurportin 1 anticorps

N° du produit ABIN2458516

Détail du produit anti-Snurportin 1 anticorps

Antigène: Snurportin 1 (SNUPN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Snurportin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNUPN.

Information d'application

Indications d'application: SNUPN antibody can be used for detection of SNUPN by ELISA at 1:62500. SNUPN antibody can be used for detection of SNUPN by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SNUPN antibody at -20 °C.

Détails sur Snurportin 1

Antigène: Snurportin 1 (SNUPN)

Autre désignation: SNUPN (SNUPN Produits)

Synonymes: anticorps rnut1, anticorps zgc:77819, anticorps wu:fc41a03, anticorps SNUPN, anticorps kpnbl, anticorps snurportin1, anticorps KPNBL, anticorps RNUT1, anticorps Snurportin1, anticorps 0610031A09Rik, anticorps Rnut1, anticorps Snupn1, anticorps snurportin 1, anticorps snupn, anticorps SNUPN, anticorps Snupn

Sujet: The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Poids moléculaire: 41 kDa

ID gène: 10073

NCBI Accession: NP_005692

UniProt: O95149

Pathways: Ribonucleoprotein Complex Subunit Organization, Protein targeting to Nucleus