A1CF anticorps

N° du produit ABIN2458553

Détail du produit anti-A1CF anticorps

Antigène: A1CF (APOBEC1 Complementation Factor (A1CF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp A1CF est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human A1CF.

Information d'application

Indications d'application: A1CF antibody can be used for detection of A1CF by ELISA at 1:1562500. A1CF antibody can be used for detection of A1CF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store A1CF antibody at -20 °C.

Détails sur A1CF

Antigène: A1CF (APOBEC1 Complementation Factor (A1CF))

Autre désignation: A1CF (A1CF Produits)

Synonymes: anticorps ACF, anticorps ACF64, anticorps ACF65, anticorps APOBEC1CF, anticorps ASP, anticorps 1810073H04Rik, anticorps Acf, anticorps A1cft, anticorps Apobec-1, anticorps acf, anticorps acf64, anticorps acf65, anticorps apobec1cf, anticorps asp, anticorps A1CF, anticorps APOBEC1 complementation factor, anticorps apobec1 complementation factor, anticorps APOBEC1 complementation factor L homeolog, anticorps A1CF, anticorps A1cf, anticorps a1cf, anticorps a1cf.L

Sujet: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.

Poids moléculaire: 65 kDa

ID gène: 29974

NCBI Accession: NP_620311

UniProt: Q9NQ94