CPB2 anticorps

N° du produit ABIN2458761

Détail du produit anti-CPB2 anticorps

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPB2.

Information d'application

Indications d'application: CPB2 antibody can be used for detection of CPB2 by ELISA at 1:1562500. CPB2 antibody can be used for detection of CPB2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CPB2 antibody at -20 °C.

Détails sur CPB2

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Autre désignation: CPB2 (CPB2 Produits)

Synonymes: anticorps CPU, anticorps PCPB, anticorps TAFI, anticorps 1110032P04Rik, anticorps 4930405E17Rik, anticorps AI255929, anticorps CPR, anticorps Cpu, anticorps pCPB, anticorps zgc:112493, anticorps carboxypeptidase B2, anticorps carboxypeptidase B2 (plasma), anticorps CPB2, anticorps Cpb2, anticorps cpb2

Sujet: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms.

Poids moléculaire: 36 kDa

ID gène: 1361

NCBI Accession: NP_001863

UniProt: Q96IY4

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis