GGCX anticorps

N° du produit ABIN2458835

Détail du produit anti-GGCX anticorps

Antigène: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GGCX est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GGCX.

Information d'application

Indications d'application: GGCX antibody can be used for detection of GGCX by ELISA at 1:1562500. GGCX antibody can be used for detection of GGCX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GGCX antibody at -20 °C.

Détails sur GGCX

Antigène: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Autre désignation: GGCX (GGCX Produits)

Synonymes: anticorps GGCX, anticorps cb751, anticorps si:ch1073-230p18.3, anticorps zgc:158736, anticorps ggcx, anticorps GGC, anticorps vkcfd1, anticorps CG13927, anticorps DgammaC, anticorps Dmel\\CG13927, anticorps dGC, anticorps dgammaC, anticorps gammaC, anticorps VKCFD1, anticorps gamma-glutamyl carboxylase, anticorps gamma-glutamyl carboxylase L homeolog, anticorps GGCX, anticorps ggcx, anticorps GC, anticorps sce5891, anticorps ggcx.L, anticorps Ggcx

Sujet: GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).

Poids moléculaire: 87 kDa

ID gène: 2677

NCBI Accession: NP_000812

UniProt: P38435

Pathways: SARS-CoV-2 Protein Interactome