ATP2B4 anticorps

N° du produit ABIN2458841

Détail du produit anti-ATP2B4 anticorps

Antigène: ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP2B4 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP2B4.

Information d'application

Indications d'application: ATP2B4 antibody can be used for detection of ATP2B4 by ELISA at 1:1562500. ATP2B4 antibody can be used for detection of ATP2B4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP2B4 antibody at -20 °C.

Détails sur ATP2B4

Antigène: ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))

Autre désignation: ATP2B4 (ATP2B4 Produits)

Synonymes: anticorps ATP2B2, anticorps MXRA1, anticorps PMCA4, anticorps PMCA4b, anticorps PMCA4x, anticorps atp2b2, anticorps atp2b3, anticorps mxra1, anticorps pmca4, anticorps pmca4b, anticorps pmca4x, anticorps zgc:152801, anticorps ATP2B4, anticorps ATP2B1, anticorps Pmca4, anticorps ATPase plasma membrane Ca2+ transporting 4, anticorps ATPase, Ca++ transporting, plasma membrane 4 L homeolog, anticorps ATPase, Ca++ transporting, plasma membrane 4, anticorps ATP2B4, anticorps atp2b4.L, anticorps atp2b4, anticorps Atp2b4

Sujet: ATP2B4 belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B4 is the plasma membrane calcium ATPase isoform 4.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 129 kDa

ID gène: 493

NCBI Accession: NP_001001396

UniProt: B1APW5

Pathways: Ribonucleoside Biosynthetic Process