CPT1A anticorps

N° du produit ABIN2458893

Détail du produit anti-CPT1A anticorps

Antigène: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPT1A est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPT1A.

Information d'application

Indications d'application: CPT1A antibody can be used for detection of CPT1A by ELISA at 1:312500. CPT1A antibody can be used for detection of CPT1A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CPT1A antibody at -20 °C.

Détails sur CPT1A

Antigène: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Autre désignation: CPT1A (CPT1A Produits)

Synonymes: anticorps MGC53498, anticorps CPT1, anticorps CPT1-L, anticorps L-CPT1, anticorps L-CPTI, anticorps si:dkey-56p7.8, anticorps C730027G07, anticorps CPTI, anticorps Cpt1, anticorps CPT-Ia, anticorps carnitine palmitoyltransferase 1A (liver) L homeolog, anticorps carnitine palmitoyltransferase 1A, anticorps carnitine palmitoyltransferase 1A (liver), anticorps carnitine palmitoyltransferase 1Aa (liver), anticorps carnitine palmitoyltransferase 1a, liver, anticorps cpt1a.L, anticorps CPT1A, anticorps cpt1a, anticorps cpt1aa, anticorps Cpt1a

Sujet: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 86 kDa

ID gène: 1374

NCBI Accession: NP_001027017

UniProt: P50416

Pathways: AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process