Transferrin Receptor 2 anticorps

N° du produit ABIN2458932

Détail du produit anti-Transferrin Receptor 2 anticorps

Antigène: Transferrin Receptor 2 (TFR2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transferrin Receptor 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFR2.

Information d'application

Indications d'application: TFR2 antibody can be used for detection of TFR2 by ELISA at 1:62500. TFR2 antibody can be used for detection of TFR2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TFR2 antibody at -20 °C.

Détails sur Transferrin Receptor 2

Antigène: Transferrin Receptor 2 (TFR2)

Autre désignation: TFR2 (TFR2 Produits)

Synonymes: anticorps TFR2, anticorps Trfr2, anticorps HFE3, anticorps TFRC2, anticorps zgc:123043, anticorps transferrin receptor 2, anticorps TFR2, anticorps Tfr2, anticorps tfr2

Sujet: TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 89 kDa

ID gène: 7036

NCBI Accession: NP_003218

UniProt: Q9UP52

Pathways: Transition Metal Ion Homeostasis