IL11RA anticorps

N° du produit ABIN2459023

Détail du produit anti-IL11RA anticorps

Antigène: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL11RA est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL11RA.

Information d'application

Indications d'application: IL11RA antibody can be used for detection of IL11RA by ELISA at 1:12500. IL11RA antibody can be used for detection of IL11RA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store IL11RA antibody at -20 °C.

Détails sur IL11RA

Antigène: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Autre désignation: IL11RA (IL11RA Produits)

Synonymes: anticorps CRSDA, anticorps fi26e06, anticorps il-11ra, anticorps wu:fi26e06, anticorps AI314697, anticorps GP130, anticorps Il-11ra, anticorps Il11ra, anticorps Il11ra2, anticorps NR1, anticorps interleukin 11 receptor subunit alpha, anticorps interleukin 11 receptor, alpha, anticorps interleukin 11 receptor subunit alpha 1, anticorps interleukin 11 receptor, alpha chain 1, anticorps IL11RA, anticorps il11ra, anticorps Il11ra1, anticorps Il11ra

Sujet: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA is the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.

Poids moléculaire: 43 kDa

ID gène: 3590

NCBI Accession: NP_004503

UniProt: Q14626

Pathways: Signalistation JAK/STAT, Growth Factor Binding