STING/TMEM173 anticorps

N° du produit ABIN2459160

Détail du produit anti-STING/TMEM173 anticorps

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STING/TMEM173 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMEM173.

Information d'application

Indications d'application: TMEM173 antibody can be used for detection of TMEM173 by ELISA at 1:62500. TMEM173 antibody can be used for detection of TMEM173 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TMEM173 antibody at -20 °C.

Détails sur STING/TMEM173

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Autre désignation: TMEM173 (TMEM173 Produits)

Synonymes: anticorps ERIS, anticorps MITA, anticorps MPYS, anticorps NET23, anticorps STING, anticorps 2610307O08Rik, anticorps Mita, anticorps RGD1562552, anticorps transmembrane protein 173, anticorps TMEM173, anticorps Tmem173

Sujet: TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

Poids moléculaire: 42 kDa

ID gène: 340061

NCBI Accession: NP_938023

UniProt: Q86WV6

Pathways: Activation of Innate immune Response