SIN3B
Reactivité: Souris, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
SIN3B antibody can be used for detection of SIN3B by ELISA at 1:312500. SIN3B antibody can be used for detection of SIN3B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store SIN3B antibody at -20 °C.
Antigène
SIN3B
(SIN3 Transcription Regulator Homolog B (SIN3B))
anticorps fj63d08, anticorps si:dkey-6n6.6, anticorps wu:fj63d08, anticorps 2810430C10Rik, anticorps SIN3 transcription regulator family member B, anticorps SIN3 transcription regulator family member B S homeolog, anticorps transcriptional regulator, SIN3B (yeast), anticorps sin3b, anticorps SIN3B, anticorps sin3b.S, anticorps Sin3b
Sujet
SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.