CYP27A1 anticorps

N° du produit ABIN2459496

Détail du produit anti-CYP27A1 anticorps

Antigène: CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP27A1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP27A1.

Information d'application

Indications d'application: CYP27A1 antibody can be used for detection of CYP27A1 by ELISA at 1:62500. CYP27A1 antibody can be used for detection of CYP27A1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CYP27A1 antibody at -20 °C.

Détails sur CYP27A1

Antigène: CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

Autre désignation: CYP27A1 (CYP27A1 Produits)

Synonymes: anticorps CP27, anticorps CTX, anticorps CYP27, anticorps Cyp27, anticorps P450C27, anticorps 1300013A03Rik, anticorps cytochrome P450 family 27 subfamily A member 1, anticorps cytochrome P450, family 27, subfamily a, polypeptide 1, anticorps cytochrome P450, family 27, subfamily A, polypeptide 1, anticorps sterol 26-hydroxylase, mitochondrial, anticorps CYP27A1, anticorps Cyp27a1, anticorps cyp27a1

Sujet: CYP27A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 57 kDa

ID gène: 1593

NCBI Accession: NP_000775

UniProt: Q02318