Gephyrin anticorps

N° du produit ABIN2459504

Détail du produit anti-Gephyrin anticorps

Antigène: Gephyrin (GPHN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Gephyrin est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GPHN.

Information d'application

Indications d'application: GPHN antibody can be used for detection of GPHN by ELISA at 1:1562500. GPHN antibody can be used for detection of GPHN by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GPHN antibody at -20 °C.

Détails sur Gephyrin

Antigène: Gephyrin (GPHN)

Autre désignation: GPHN (GPHN Produits)

Synonymes: anticorps 5730552E08Rik, anticorps AI662856, anticorps BC027112, anticorps C230040D23, anticorps GPH, anticorps GPHRYN, anticorps geph, anticorps Geph, anticorps GPHN, anticorps GEPH, anticorps HKPX1, anticorps gpgb1, anticorps DKFZp459M0825, anticorps gephyrin, anticorps gephyrin L homeolog, anticorps gephyrin a, anticorps Gphn, anticorps GPHN, anticorps gphn.L, anticorps gphna, anticorps PTRG_08978, anticorps VDBG_00775, anticorps Tsp_03043, anticorps gphn

Sujet: GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

Poids moléculaire: 80 kDa

ID gène: 10243

NCBI Accession: NP_001019389

UniProt: Q9NQX3

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development