CYP11A1
Reactivité: Porc
WB, IHC, ICC, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
CYP11A1 antibody can be used for detection of CYP11A1 by ELISA at 1:1562500. CYP11A1 antibody can be used for detection of CYP11A1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store CYP11A1 antibody at -20 °C.
Antigène
CYP11A1
(Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
anticorps CYP11A, anticorps CYP11A1, anticorps CYPXIA1, anticorps P450SCC, anticorps Cyp11a, anticorps Cypxia1, anticorps D9Ertd411e, anticorps P450scc, anticorps Scc, anticorps cscc, anticorps P450(scc), anticorps SSC, anticorps cytochrome P450 family 11 subfamily A member 1, anticorps cholesterol side-chain cleavage enzyme, mitochondrial-like, anticorps cytochrome P450 cholesterol side-chain cleavage, anticorps cytochrome P450, family 11, subfamily a, polypeptide 1, anticorps cytochrome P450, family 11, subfamily A, polypeptide 1, anticorps CYP11A1, anticorps LOC101827747, anticorps Cyp11a1
Sujet
CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11A1 localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.