MPP7 anticorps

N° du produit ABIN2459648

Détail du produit anti-MPP7 anticorps

Antigène: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPP7 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MPP7.

Information d'application

Indications d'application: MPP7 antibody can be used for detection of MPP7 by ELISA at 1:62500. MPP7 antibody can be used for detection of MPP7 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MPP7 antibody at -20 °C.

Détails sur MPP7

Antigène: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Autre désignation: MPP7 (MPP7 Produits)

Synonymes: anticorps 1110068J02Rik, anticorps 2810038M04Rik, anticorps 5430426E14Rik, anticorps AI415104, anticorps Gm955, anticorps dlg3, anticorps hmp, anticorps membrane palmitoylated protein 7, anticorps membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7), anticorps membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7), anticorps MPP7, anticorps Mpp7, anticorps mpp7a

Sujet: MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. MPP7 is involved in the assembly of protein complexes at sites of cell-cell contact.Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]).

Poids moléculaire: 65 kDa

ID gène: 143098

NCBI Accession: NP_775767

UniProt: Q5T2T1

Pathways: Cell-Cell Junction Organization