KPNA3 anticorps

N° du produit ABIN2459794

Détail du produit anti-KPNA3 anticorps

Antigène: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KPNA3.

Information d'application

Indications d'application: KPNA3 antibody can be used for detection of KPNA3 by ELISA at 1:12500. KPNA3 antibody can be used for detection of KPNA3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KPNA3 antibody at -20 °C.

Détails sur KPNA3

Antigène: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Autre désignation: KPNA3 (KPNA3 Produits)

Synonymes: anticorps IPOA4, anticorps si:dz79f24.2, anticorps importin, anticorps SRP1, anticorps SRP1gamma, anticorps SRP4, anticorps hSRP1, anticorps ipoa4, anticorps srp1, anticorps srp1gamma, anticorps srp4, anticorps karyopherin (importin) alpha 3, anticorps karyopherin alpha 3 (importin alpha 4), anticorps karyopherin subunit alpha 3, anticorps karyopherin alpha 3 (importin alpha 4) L homeolog, anticorps Kpna3, anticorps kpna3, anticorps KPNA3, anticorps kpna3.L

Sujet: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3 is a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggest that karyopherin alpha-3 may be involved in the nuclear transport system.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 58 kDa

ID gène: 3839

NCBI Accession: NP_002258

UniProt: O00505

Pathways: Protein targeting to Nucleus