FAM120A
Reactivité: Humain
WB, ELISA, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
FAM120A antibody can be used for detection of FAM120A by ELISA at 1:312500. FAM120A antibody can be used for detection of FAM120A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store FAM120A antibody at -20 °C.
Antigène
FAM120A
(Family with Sequence Similarity 120A (FAM120A))
anticorps MGC89333, anticorps fam120a, anticorps C9orf10, anticorps Ossa, anticorps DNAPTP1, anticorps DNAPTP5, anticorps OSSA, anticorps RGD1306643, anticorps family with sequence similarity 120A, anticorps family with sequence similarity 120, member A, anticorps fam120a, anticorps Fam120a, anticorps FAM120A
Sujet
FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.