TFAP2B anticorps

N° du produit ABIN2459994

Détail du produit anti-TFAP2B anticorps

Antigène: TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAP2B est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFAP2B.

Information d'application

Indications d'application: TFAP2B antibody can be used for detection of TFAP2B by ELISA at 1:62500. TFAP2B antibody can be used for detection of TFAP2B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TFAP2B antibody at -20 °C.

Détails sur TFAP2B

Antigène: TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))

Autre désignation: TFAP2B (TFAP2B Produits)

Synonymes: anticorps TFAP2B, anticorps AP-2B, anticorps Tcfap2b, anticorps AP2, anticorps si:dkey-5e16.1, anticorps zgc:110163, anticorps AP-1beta1, anticorps AP-2beta, anticorps AP-beta1, anticorps AP1beta1, anticorps AP2beta2, anticorps BAD1, anticorps BAP, anticorps Beta-adaptin, anticorps CG12532, anticorps Dmel\\CG12532, anticorps bap, anticorps beta1/2, anticorps cg12532, anticorps AI606113, anticorps AP-2(beta), anticorps E130018K07Rik, anticorps AP2-B, anticorps ap-2b, anticorps ap2-b, anticorps tfap2beta, anticorps transcription factor AP-2 beta, anticorps beta-adaptin, anticorps putative beta-adaptin, anticorps Adaptor Protein complex 1/2, beta subunit, anticorps transcription factor AP-2 beta L homeolog, anticorps TFAP2B, anticorps Tfap2b, anticorps tfap2b, anticorps Tc00.1047053509799.10, anticorps Tc00.1047053506247.200, anticorps LINJ_36_7080, anticorps LBRM_35_7120, anticorps LMJF_36_6770, anticorps Tcfap2b, anticorps AP-1-2beta, anticorps Tsp_09571, anticorps tfap2b.L

Sujet: TFAP2B belongs to the AP-2 family which is developmentally regulated and have distinct overlapping functions in the regulation of many genes governing growth and differentiation. TFAP2B binds DNA as a dimmer and can form homodimers or heterodimers with other AP-2 family members. It may be a candidate for conferring susceptibility to type 2 didabetes. This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-144 AU141084.1 1-144 145-1684 BC037225.1 1-1540 1685-5370 AL049693.16 11928-15613 5371-5770 BU738725.1 18-417 c

Poids moléculaire: 50 kDa

ID gène: 7021

NCBI Accession: NP_003212

UniProt: Q92481

Pathways: Carbohydrate Homeostasis, Synaptic Membrane