APRT anticorps

N° du produit ABIN2460045

Détail du produit anti-APRT anticorps

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APRT est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APRT.

Information d'application

Indications d'application: APRT antibody can be used for detection of APRT by ELISA at 1:312500. APRT antibody can be used for detection of APRT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store APRT antibody at -20 °C.

Détails sur APRT

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Autre désignation: APRT (APRT Produits)

Synonymes: anticorps Tb07.43M14.200, anticorps Tb07.43M14.180, anticorps C85684, anticorps AMP, anticorps APRTD, anticorps adenine phosphoribosyltransferase, anticorps adenine phosphoribosyl transferase, anticorps CND05020, anticorps Tb927.7.1790, anticorps Tb927.7.1780, anticorps Arnit_0941, anticorps Saut_1231, anticorps Fbal_1180, anticorps PH_RS07970, anticorps PF_RS08760, anticorps PAB_RS02560, anticorps Aprt, anticorps APRT

Sujet: Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 20 kDa

ID gène: 353

NCBI Accession: NP_000476

UniProt: P07741

Pathways: Ribonucleoside Biosynthetic Process