DMRT1 anticorps

N° du produit ABIN2460120

Détail du produit anti-DMRT1 anticorps

Antigène: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMRT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DMRT1.

Information d'application

Indications d'application: DMRT1 antibody can be used for detection of DMRT1 by ELISA at 1:12500. DMRT1 antibody can be used for detection of DMRT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DMRT1 antibody at -20 °C.

Détails sur DMRT1

Antigène: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Autre désignation: DMRT1 (DMRT1 Produits)

Synonymes: anticorps DMT1, anticorps DMRT1, anticorps zgc:136676, anticorps dmrt1, anticorps dmrt1-alpha, anticorps dmt1, anticorps dmrt1-beta, anticorps xdmrt1, anticorps doublesex and mab-3 related transcription factor 1, anticorps doublesex and mab-3 related transcription factor 1 L homeolog, anticorps doublesex and mab-3 related transcription factor 1 S homeolog, anticorps DMRT1, anticorps Dmrt1, anticorps dmrt1, anticorps dmrt1.L, anticorps dmrt1.S

Sujet: The gene encodes the DMRT1 protein is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. This suggested that DMRT1 may be required for testis development.This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 39 kDa

ID gène: 1761

NCBI Accession: NP_068770

UniProt: Q9Y5R6