NFKBIL2 anticorps

N° du produit ABIN2460131

Détail du produit anti-NFKBIL2 anticorps

Antigène: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFKBIL2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFKBIL2.

Information d'application

Indications d'application: NFKBIL2 antibody can be used for detection of NFKBIL2 by ELISA at 1:62500. NFKBIL2 antibody can be used for detection of NFKBIL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFKBIL2 antibody at -20 °C.

Détails sur NFKBIL2

Antigène: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Autre désignation: NFKBIL2 (NFKBIL2 Produits)

Synonymes: anticorps IKBR, anticorps NFKBIL2, anticorps 2810439M11Rik, anticorps Nfkbil2, anticorps im:7145273, anticorps nfkbil2, anticorps tonsl, anticorps tonsoku like, DNA repair protein, anticorps tonsoku-like, DNA repair protein, anticorps TONSL, anticorps Tonsl, anticorps tonsl

Sujet: NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

Poids moléculaire: 133 kDa

ID gène: 4796

NCBI Accession: NP_038460

UniProt: Q96HA7

Pathways: Maintenance of Protein Location