SNF8 anticorps
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- Antigène Voir toutes SNF8 Anticorps
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SNF8 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNF8.
- Top Product
- Discover our top product SNF8 Anticorps primaire
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- Indications d'application
- SNF8 antibody can be used for detection of SNF8 by ELISA at 1:1562500. SNF8 antibody can be used for detection of SNF8 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SNF8 antibody at -20 °C.
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- Antigène
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- Autre désignation
- SNF8 (SNF8 Produits)
- Synonymes
- anticorps d11moh34, anticorps vps22, anticorps Dot3, anticorps EAP30, anticorps VPS22, anticorps D11moh34, anticorps RGD1310144, anticorps D11Moh34, anticorps D11MOH34, anticorps zgc:101578, anticorps SNF8, ESCRT-II complex subunit, anticorps eap30 subunit of ell complex, putative, anticorps EAP30 subunit of ELL complex, anticorps SNF8, ESCRT-II complex subunit S homeolog, anticorps SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae), anticorps snf8, anticorps TA17290, anticorps TVAG_107410, anticorps Bm1_05145, anticorps SNF8, anticorps Snf8, anticorps snf8.S
- Sujet
- ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).
- Poids moléculaire
- 29 kDa
- ID gène
- 11267
- NCBI Accession
- NP_009172
- UniProt
- Q96H20
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