Paired Box 3 anticorps

N° du produit ABIN2460551

Détail du produit anti-Paired Box 3 anticorps

Antigène: Paired Box 3 (PAX3)

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Paired Box 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX3.

Information d'application

Indications d'application: PAX3 antibody can be used for detection of PAX3 by ELISA at 1:1562500. PAX3 antibody can be used for detection of PAX3 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAX3 antibody at -20 °C.

Détails sur Paired Box 3

Antigène: Paired Box 3 (PAX3)

Autre désignation: PAX3 (PAX3 Produits)

Synonymes: anticorps PAX3, anticorps cdhs, anticorps hup2, anticorps pax-3, anticorps ws1, anticorps xpax3, anticorps Pax3, anticorps pax3, anticorps pax3b, anticorps xPax3-B, anticorps CDHS, anticorps HUP2, anticorps WS1, anticorps WS3, anticorps Pax-3, anticorps Sp, anticorps splotch, anticorps zgc:92547, anticorps paired box 3, anticorps paired box 3 L homeolog, anticorps paired box 3a, anticorps PAX3, anticorps pax3, anticorps pax3.L, anticorps Pax3, anticorps pax3a

Sujet: PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2,13) (q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2,13) (q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Poids moléculaire: 53 kDa, 53 kDa, 56 kDa

ID gène: 5077

NCBI Accession: NP_852122

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation