CIAO1 anticorps

N° du produit ABIN2460941

Détail du produit anti-CIAO1 anticorps

Antigène: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIAO1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WDR39.

Information d'application

Indications d'application: WDR39 antibody can be used for detection of WDR39 by ELISA at 1:62500. WDR39 antibody can be used for detection of WDR39 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store WDR39 antibody at -20 °C.

Détails sur CIAO1

Antigène: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Autre désignation: WDR39 (CIAO1 Produits)

Synonymes: anticorps CG12797, anticorps Dmel\\CG12797, anticorps DDBDRAFT_0190506, anticorps DDBDRAFT_0266672, anticorps DDB_0190506, anticorps DDB_0266672, anticorps CIA1, anticorps WDR39, anticorps AW210570, anticorps Wdr39, anticorps wdr39, anticorps zgc:55911, anticorps zgc:77394, anticorps CG12797 gene product from transcript CG12797-RA, anticorps WD40 protein Ciao1, anticorps CIAO1, anticorps WD40 repeat-containing protein, anticorps cytosolic iron-sulfur assembly component 1, anticorps cytosolic iron-sulfur protein assembly 1, anticorps Ciao1, anticorps cgd1_2230, anticorps CC1G_05316, anticorps ciao1, anticorps CIAO1

Sujet: WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.

Poids moléculaire: 38 kDa

ID gène: 9391

NCBI Accession: NP_004795

UniProt: O76071