ID4 anticorps

N° du produit ABIN2461635

Détail du produit anti-ID4 anticorps

Antigène: ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ID4 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ID4.

Information d'application

Indications d'application: ID4 antibody can be used for detection of ID4 by ELISA at 1:1562500. ID4 antibody can be used for detection of ID4 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ID4 antibody at -20 °C.

Détails sur ID4

Antigène: ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))

Autre désignation: ID4 (ID4 Produits)

Synonymes: anticorps Idb4, anticorps bHLHb27, anticorps cb547, anticorps fb77d04, anticorps sb:cb547, anticorps wu:fb77d04, anticorps zgc:123214, anticorps bhlhb27, anticorps id4, anticorps id4a, anticorps idb4, anticorps IDB4, anticorps inhibitor of DNA binding 4, anticorps inhibitor of DNA binding 4, HLH protein, anticorps inhibitor of DNA binding 4, HLH protein S homeolog, anticorps Id4, anticorps id4, anticorps id4.S, anticorps ID4

Sujet: Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995).

Poids moléculaire: 17 kDa

ID gène: 3400

NCBI Accession: NP_001537

UniProt: P47928