SMARCE1
Reactivité: Humain, Souris, Rat, Lapin, Chien, Cheval, Boeuf (Vache), Cobaye, Porc
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
SMARCE1 antibody can be used for detection of SMARCE1 by ELISA at 1:12500. SMARCE1 antibody can be used for detection of SMARCE1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMARCE1 antibody at -20 °C.
Antigène
SMARCE1
(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
anticorps BAF57, anticorps XBaf57, anticorps MGC52696, anticorps MGC69429, anticorps MGC81726, anticorps SMARCE1, anticorps DKFZp459O2235, anticorps fb54d11, anticorps wu:fb33d02, anticorps wu:fb54d11, anticorps Baf57, anticorps 2810417B20Rik, anticorps 5830412H02Rik, anticorps 9030408N19Rik, anticorps Baf27, anticorps RGD1304726, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 L homeolog, anticorps smarce1, anticorps SMARCE1, anticorps smarce1.L, anticorps Smarce1
Sujet
SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.