NR1D2 anticorps

N° du produit ABIN2461740

Détail du produit anti-NR1D2 anticorps

Antigène: NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1D2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1D2.

Information d'application

Indications d'application: NR1D2 antibody can be used for detection of NR1D2 by ELISA at 1:312500. NR1D2 antibody can be used for detection of NR1D2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR1D2 antibody at -20 °C.

Détails sur NR1D2

Antigène: NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))

Autre désignation: NR1D2 (NR1D2 Produits)

Synonymes: anticorps BD73, anticorps EAR-1R, anticorps RVR, anticorps HZF-2, anticorps Rev-erb, anticorps REV-ERBB, anticorps NR1D2, anticorps rvr, anticorps bd73, anticorps hzf2, anticorps ear-1r, anticorps hs.37288, anticorps NR1D2-A, anticorps Reverbbeta-A, anticorps reverbb1, anticorps reverbb, anticorps reverbb2, anticorps zgc:92019, anticorps nuclear receptor subfamily 1 group D member 2, anticorps nuclear receptor subfamily 1, group D, member 2, anticorps nuclear receptor subfamily 1, group D, member 2a, anticorps nuclear receptor subfamily 1, group D, member 2b, anticorps NR1D2, anticorps Nr1d2, anticorps nr1d2, anticorps nr1d2a, anticorps nr1d2b

Sujet: NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.

Poids moléculaire: 65 kDa

ID gène: 9975

NCBI Accession: NP_005117

UniProt: Q14995

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway