SMARCAL1
Reactivité: Humain, Souris, Rat
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
SMARCAL1 antibody can be used for detection of SMARCAL1 by ELISA at 1:312500. SMARCAL1 antibody can be used for detection of SMARCAL1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMARCAL1 antibody at -20 °C.
anticorps SMARCAL1, anticorps im:7145331, anticorps si:ch211-239d11.1, anticorps harp, anticorps hharp, anticorps 6030401P21Rik, anticorps AI851716, anticorps Mharp, anticorps HARP, anticorps HHARP, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 L homeolog, anticorps SMARCAL1, anticorps smarcal1, anticorps Smarcal1, anticorps smarcal1.L
Sujet
SMARCAL1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Mutations in SMARCAL1 gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.