KLHL3 anticorps

N° du produit ABIN2461880

Détail du produit anti-KLHL3 anticorps

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KLHL3.

Information d'application

Indications d'application: KLHL3 antibody can be used for detection of KLHL3 by ELISA at 1:62500. KLHL3 antibody can be used for detection of KLHL3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KLHL3 antibody at -20 °C.

Détails sur KLHL3

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Autre désignation: KLHL3 (KLHL3 Produits)

Synonymes: anticorps 7530408C15Rik, anticorps AI430941, anticorps EG627648, anticorps PHA2D, anticorps RGD1565218, anticorps kelch like family member 3, anticorps kelch-like 3, anticorps kelch-like family member 3, anticorps KLHL3, anticorps Klhl3

Sujet: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.

Poids moléculaire: 65 kDa

ID gène: 26249

NCBI Accession: NP_059111

UniProt: Q9UH77