NR2F2 anticorps

N° du produit ABIN2461905

Détail du produit anti-NR2F2 anticorps

Antigène: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2F2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2F2.

Information d'application

Indications d'application: NR2F2 antibody can be used for detection of NR2F2 by ELISA at 1:312500. NR2F2 antibody can be used for detection of NR2F2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR2F2 antibody at -20 °C.

Détails sur NR2F2

Antigène: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Autre désignation: NR2F2 (NR2F2 Produits)

Synonymes: anticorps nr2f2, anticorps MGC52954, anticorps ARP1, anticorps COUPTFB, anticorps COUPTFII, anticorps NF-E3, anticorps NR2F1, anticorps SVP40, anticorps TFCOUP2, anticorps 2700033K02Rik, anticorps 9430015G03Rik, anticorps ARP-1, anticorps Aporp1, anticorps COUP-TF2, anticorps COUP-TFII, anticorps EAR3, anticorps Tcfcoup2, anticorps Tfcoup2, anticorps fc94g08, anticorps svp40, anticorps svp[40], anticorps wu:fc94g08, anticorps nuclear receptor subfamily 2 group F member 2 L homeolog, anticorps Nr2f2 protein, anticorps nuclear receptor subfamily 2 group F member 2, anticorps nuclear receptor subfamily 2, group F, member 2, anticorps nr2f2.L, anticorps nr2f2, anticorps NR2F2, anticorps Nr2f2

Sujet: NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.

Poids moléculaire: 45 kDa

ID gène: 7026

NCBI Accession: NP_066285

UniProt: P24468

Pathways: Steroid Hormone Mediated Signaling Pathway