Interleukin enhancer-binding factor 3 (ILF3) anticorps

N° du produit ABIN2462163

Détail du produit

Antigène: Interleukin enhancer-binding factor 3 (ILF3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ILF3.

Information d'application

Indications d'application: ILF3 antibody can be used for detection of ILF3 by ELISA at 1:62500. ILF3 antibody can be used for detection of ILF3 by western blot at 0.0625 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ILF3 antibody at -20 °C.

Détail du antigène

Antigène: Interleukin enhancer-binding factor 3 (ILF3)

Autre désignation: ILF3 (ILF3 Produits)

Synonymes: anticorps CBTF, anticorps DRBF, anticorps DRBP76, anticorps MMP4, anticorps MPHOSPH4, anticorps MPP4, anticorps NF-AT-90, anticorps NF110, anticorps NF110b, anticorps NF90, anticorps NF90a, anticorps NF90b, anticorps NFAR, anticorps NFAR-1, anticorps NFAR2, anticorps TCP110, anticorps TCP80, anticorps MBII-26, anticorps ilf3, anticorps wu:fb37d07, anticorps wu:fb94b02, anticorps zgc:77030, anticorps 4F.1, anticorps cbtf122, anticorps ilf3-A, anticorps ubp3, anticorps ubp4, anticorps xilf3, anticorps interleukin enhancer binding factor 3, anticorps interleukin enhancer binding factor 3b, anticorps interleukin enhancer binding factor 3 S homeolog, anticorps ILF3, anticorps Ilf3, anticorps ilf3b, anticorps ilf3.S

Sujet: ILF3 may facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. ILF3 can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. ILF3 can regulate protein arginine N-methyltransferase 1 activity. ILF3 may regulate transcription of the IL2 gene during T-cell activation. It can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.

Poids moléculaire: 76 kDa, 95 kDa, 75 kDa

ID gène: 3609

NCBI Accession: NP_004507

Pathways: M Phase